Overview
Clinical Orientation
Prostate cancer is not one clinical problem. A small, low grade tumour confined to the gland may never threaten health, whereas a high grade tumour can invade locally, spread to...
Prostate cancer is not one clinical problem. A small, low-grade tumour confined to the gland may never threaten health, whereas a high-grade tumour can invade locally, spread to bone, and progress despite androgen suppression. The NP therefore asks two questions at every stage: how dangerous is the cancer, and what burden will an intervention add? The answer depends on PSA interpreted over time, examination, MRI, biopsy grade, stage, comorbidity, life expectancy, function, and the patient's priorities.