Hemodialysis and Renal Replacement Therapy involves disruption of renal filtration, tubular function, electrolyte homeostasis, or acid-base balance specific to hemodialysis and renal replacement therapy. Connect Hemodialysis and Renal Replacement Therapy to bedside cues you will reassess first: vitals trends, work of breathing, perfusion, mentation, and pain or ischemic equivalents when relevant. NCLEX items often reward recognizing when subtle instability outweighs reassurance, then selecting nursing actions that protect airway, circulation, and neurologic status before routine tasks.