Introduction
FNP spans ages—polypharmacy appears in middle-aged multimorbidity and frail elders. WHNP may embed pregnancy or perimenopause where teratogenic or hormonal meds interact with psychotropics—still apply geriatric principles when caring for older women. PNP-PC rarely centers geriatrics, but teen polypharmacy (ADHD + asthma + OTC) appears—use weight-based reasoning and growth context; this lesson’s older-adult spine remains the default unless the stem shifts age. Medication reconciliation Every complex visit starts with one list—include OTC, supplements, and specialist changes—before you add therapy.
Questions pair falls with sedatives, hypoglycemia with insulin secretagogues, and renal injury with NSAIDs + RAAS blockade. Choose harm-reduction first when acute instability is absent but risk is cumulative. WHNP/PNP overlays • WHNP: pregnancy-safe alternatives when deprescribing teratogens; bone health when stopping long-term PPI in postmenopausal risk context. • PNP-PC: avoid applying Beers list to pediatric patients—use interaction reasoning when the stem is a child.