Overview
Overview
Gestational trophoblastic disease (GTD) is an abnormal proliferation of trophoblastic tissue.
Gestational trophoblastic disease (GTD) is an abnormal proliferation of trophoblastic tissue. The most common form is a hydatidiform mole (molar pregnancy). GTD can progress to choriocarcinoma (malignant form). It is characterized by excessively elevated beta-hCG (human chorionic gonadotropin) because the abnormal trophoblastic tissue produces large amounts of hCG. Complete mole: No fetal tissue; all chromosomes from father; 46,XX karyotype (both sets paternal); higher risk of choriocarcinoma Partial mole: Partial fetal development; extra paternal chromosome set (69,XXX or 69,XXY); lower malignant potential On the exam, writers often pair stable-sounding options with unstable data—notice the mismatch before you commit. If the stem names a license or role, reread that line; scope errors are classic trap answers even when the clinical topic is familiar. Run a 60-second scan: breathing work and oxygenation, perfusion and end organs, neuro baseline, likely infection sources, and devices that can fail quietly. When two answers feel partly right, pick the one that reduces imminent harm and matches orders for the role you were given. Train yourself to state the primary risk in one short phrase before you read...
